Nov 29, 2021  
College Catalog 2021-2022 
    
College Catalog 2021-2022
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CHEM 2270 - Organic Chemistry Laboratory

Credit Hours: 2.00


Prerequisites: CHEM 2260  with grade C or better

This laboratory class introduces students to important organic chemistry techniques used for the purification and characterization of organic compounds (e.g., crystallization, melting point, distillation, chromatography, etc.). Molecular spectroscopy (NMR, IR, etc.) is incorporated with an emphasis on structure determination. A variety of organic syntheses are carried out to give students a hands-on experience with the range of reactions discussed in lecture.

Billable Contact Hours: 5

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OUTCOMES AND OBJECTIVES
Outcome 1: Upon completion of this course, students will be able to demonstrate a working knowledge of common organic laboratory techniques.

Objectives: During the course, students will:

  1. Identify unknown samples using melting points and boiling points.
  2. Purify samples by recrystallization.
  3. Separate mixtures of compounds by distillation.
  4. Use extraction to separate mixtures of compounds.
  5. Apply thin layer chromatography (TLC) to test the progress of a reaction and the purity of a sample.
  6. Employ column chromatography to separate mixtures of compounds.
  7. Thoroughly clean glassware and work areas.
  8. Handle and dispose of hazardous waste in the proper waste receptacles.

Outcome 2: Upon completion of this course, students will be able to identify which molecular fragments are responsible for observed spectroscopic signals.

Objectives: During the course, students will:

  1. Assign peaks in an infrared spectrum of their sample.
  2. Identify which molecular fragments are responsible for the peaks in a mass spectrum of their sample.
  3. Explain the splitting pattern, integration and position of peaks in a proton nuclear magnetic resonance spectrum of their sample.

Outcome 3: Upon completion of this course, students will be able to set up, carry out, isolate, clean up and characterize the products of common organic chemistry reactions.

Objectives: During the course, students will:

  1. Carry out and identify the products of substitution reactions.
  2. Carry out and identify the products of radical reactions.
  3. Carry out and identify the products of elimination reactions.
  4. Carry out and identify the products of oxidation reactions.
  5. Carry out and identify the products of electrophilic aromatic substitution reactions.
  6. Carry out and identify the products of Grignard reactions.

Outcome 4: Upon completion of this course, students will be able to present all of their research and findings in a properly written lab report.

Objectives: During the course, students will:

  1. Research relevant topics and present background theory on the subject of interest.
  2. Maintain proper lab notes.
  3. Formulate logical procedures.
  4. Reference all literature used according to the acceptable format.
  5. Neatly present all data and observations.
  6. Discuss results and future directions.

COMMON DEGREE OUTCOMES (CDO)
• Communication: The graduate can communicate effectively for the intended purpose and audience.
• Critical Thinking: The graduate can make informed decisions after analyzing information or evidence related to the issue.
• Global Literacy: The graduate can analyze human behavior or experiences through cultural, social, political, or economic perspectives.
• Information Literacy: The graduate can responsibly use information gathered from a variety of formats in order to complete a task.
• Quantitative Reasoning: The graduate can apply quantitative methods or evidence to solve problems or make judgments.
• Scientific Literacy: The graduate can produce or interpret scientific information presented in a variety of formats.

CDO marked YES apply to this course:
Communication: YES
Critical Thinking: YES
Information Literacy: YES
Quantitative Reasoning: YES
Scientific Literacy: YES

COURSE CONTENT OUTLINE
Unit 1 - Organic Laboratory Techniques (Four Weeks)

  1. Purify an organic solid by crystallization.
  2. Identify and characterize an organic solid by melting point determination.
  3. Determine the purity of an organic solid by melting point determination.
  4. Explain the theory of melting point depression.
  5. Purify an organic liquid by simple and fractional distillation.
  6. Explain the theory of simple and fractional distillation.
  7. Identify and characterize an organic liquid by boiling point determination.
  8. Explain the theory of boiling point elevation.
  9. Isolate an organic compound by solvent extraction.
  10. Evaluate the purity of a sample by thin layer chromatography (TLC).
  11. Monitor the progress of an organic reaction by TLC.
  12. Separate a mixture into its component parts by column chromatography.
  13. Explain the theory of chromatography.

Unit 2 - Organic Spectroscopy (Four Weeks)

  1. Explain the theory of NMR spectroscopy.
  2. Explain the theory of IR spectroscopy.
  3. Explain the theory of mass spectroscopy.
  4. Explain the theory of UV-Vis spectroscopy.
  5. Prepare an organic sample for spectroscopic use and collect the spectrum of that sample.
  6. Analyze spectroscopic data in order to determine the structure of an unknown organic compound.

Unit 3 - Organic Synthesis (Eight Weeks)

  1. Design and conduct experiments to perform simple organic synthetic transformations.
    1. Alcohols to alkenes
    2. Carbonyls to alcohols by reduction
    3. Alcohols to carbonyls by oxidation
    4. Electrophilic aromatic substitution
    5. Organometallic reactions
    6. Nucleophilic substitution reactions

Primary Faculty
Tramontozzi, David
Secondary Faculty

Associate Dean
Young, Randall
Dean
Pritchett, Marie



Official Course Syllabus - Macomb Community College, 14500 E 12 Mile Road, Warren, MI 48088



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